继承和发扬祖国药剂学的成就,蜂蜡骨架颗粒可以作为口服长效剂型的一种形式,释药缓慢且均衡。颗粒的粒度及含蜡量这两种因素,独立地对生物利用度产生影响,而含蜡量起主要作用。蜂蜡来源方便,特别是食用无害而较国外近年来用作骨架材料的合成高分子物质优越。颗粒的生物利用度较原蜡丸提高很多,对一般的非剧毒药也具有实用意义。 Inheritance and development of the achievements of the motherland pharmacy, beeswax skeleton particles can be used as a form of oral long-acting formulations, slow and balanced release. Particle size and wax content of these two factors independently affect the bioavailability, while the amount of wax play a major role. Beeswax source easy, especially harmless to eat and abroad than in recent years as a skeleton material of synthetic polymers superior. Bioavailability of particles than the original wax pills to improve a lot of non-toxic drugs in general also have practical significance.