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目的 :用病理组织学对照观察探讨大肠癌数字血管造影 ( DSA)表现和介入化疗 ( TAC)疗效及其相互之间的关系。 资料与方法 :96例大肠癌病例经术前 DSA及 TAC,2～ 4周后行肿瘤手术切除 ,与 40例单纯手术切除病例进行病理组织学对照观察。 结果 :DSA检查示大肠癌肿瘤血管染色发生率 ( 5 5 /96 )占 5 7.3% ,肿瘤血管染色发生率与肿瘤的恶性程度、侵犯深度及肿瘤大小呈正相关。介入化疗组细胞坏死、间质改变及血管内膜炎的发生率及严重程度明显高于对照组。造影中肿瘤血管染色的发生率与血管内膜炎的发生率有显著差异 ,而与细胞坏死的程度差异不显著。 结论 :DSA可以帮助判断大肠肿瘤的恶性程度、侵犯深度及肿瘤大小。无论造影时有无肿瘤血管染色 ,介入化疗对于大肠癌均有明显的疗效
OBJECTIVE: To investigate the relationship between digital angiography (DSA) and the efficacy of interventional chemotherapy (TAC) in colorectal cancer by histopathological observation. Materials and Methods: 96 cases of colorectal cancer patients underwent preoperative DSA and TAC, 2 to 4 weeks after tumor resection, and 40 cases of simple surgical resection for histopathological observation. Results: DSA showed that the incidence of colorectal cancer vascular staining (5 5/96) accounted for 53.3%. The incidence of tumor vascular staining was positively correlated with the malignancy, depth of invasion and tumor size. Interventional chemotherapy group of cell necrosis, interstitial changes and the incidence of vascular endocarditis and the severity was significantly higher than the control group. Angiography in the incidence of tumor vascular staining and the incidence of endocarditis have significant differences, but not with the degree of cell necrosis was not significant. Conclusion: DSA can help determine the degree of malignancy of colorectal cancer, depth of invasion and tumor size. Whether tumor angiogenesis staining, interventional chemotherapy for colorectal cancer have a significant effect