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目的采用前列腺素欣普贝生、小水囊、缩宫素三种方法促宫颈成熟及引产进行对照,观察其临床效果。方法采用对比方法对150例孕足月初产妇,随机分为三组,比较三组产妇的宫颈评分、临产及分娩情况及对胎儿及新生儿的影响。结果 A组有效率为94%,B组(小水囊组)有效率为86%,C组:有效率为4%。A组与C组比较,差异有统计学意义(P<0.01),与B组相比,差异无显著性(P>0.05),但效果较B组好。B组与C组比较,差异有统计学意义(P<0.01)。结论新贝普生及小水囊促宫颈成熟及引产两种方法均是安全,有效的方法,临床应用成功率高,普贝生价格贵,但效果较小水囊好,小水囊方法效果好且经济,特别适合基层医院使用。缩宫素促宫颈成熟及引产效果不佳。
Objective To investigate the clinical effects of prostaglandin-thioprene, small water sac and oxytocin to promote cervical ripening and induction of labor. Methods 150 cases of first trimester pregnancy were randomly divided into three groups according to the comparative method. The cervical scores, labor and delivery and the effects on the fetus and newborn in the three groups were compared. Results The effective rate of group A was 94%, that of group B (small water sac) was 86%, and that of group C was 4%. The difference between group A and group C was statistically significant (P <0.01). There was no significant difference between group A and group C (P> 0.05), but the effect was better than group B. B group and C group, the difference was statistically significant (P <0.01). Conclusions The two new methods are effective and safe for cervix maturation and induction of labor. The success rate of clinical application is high, Pébison is more expensive, but less effective. Good and economical, especially suitable for primary hospital use. Oxytocin promote cervical ripening and induction of labor is not good.