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目的:综述近十几年来中药药动学研究中出现的新理论与新方法。方法:查阅国内外相关文献,对新理论与新方法及其应用作较详细的介绍。结果:证治药动学、胃肠药动学、特征图谱药动学等是近十年来出现或发展较快的中药药动学理论;中药血药浓度法、生物效应法等是应用较多的方法和技术,这两者的有机结合提升了中药体内变化的研究水平。结论:中药药动学新理论与新方法的出现和应用,丰富和发展了中医药的方药理论,为中药及其复方在体内的动态变化研究提供了有力的工具。
OBJECTIVE: To summarize the new theories and methods emerging in the research of pharmacokinetics of traditional Chinese medicine in recent ten years. Methods: Access to relevant literature at home and abroad, the new theory and new methods and their applications in more detail. Results: The TCM pharmacokinetics theory of traditional Chinese medicine appeared or developed rapidly in recent ten years, such as TCM pharmacokinetics, gastrointestinal pharmacokinetics, and pharmacokinetics of TCM, and more were applied Methods and techniques, the organic combination of the two enhances the level of research on the in vivo changes of traditional Chinese medicine. Conclusion: The emergence and application of new theories and methods of pharmacokinetics in traditional Chinese medicine have enriched and developed the prescription theory of traditional Chinese medicine, and provided a powerful tool for the study of the dynamic changes of traditional Chinese medicine and its compounds in vivo.