论文部分内容阅读
肿瘤细胞组织上常有一些生长抑素受体的过表达,奥曲肽及其衍生物与生长抑素受体(SSTR)能够高特异性地结合。因此,应用18F标记的奥曲肽及其衍生物作为肿瘤示踪剂,对生长抑素受体阳性肿瘤进行诊断具有重要的意义。为开发一种能够高效快速合成的18F标记的糖基化奥曲肽衍生
Some somatostatin receptors are overexpressed in tumor cells. Octreotide and its derivatives can bind with somatostatin receptor (SSTR) with high specificity. Therefore, the use of 18F-labeled octreotide and its derivatives as tumor tracer, the diagnosis of somatostatin receptor-positive tumors is of great significance. To develop a 18F-labeled glycosylated octreotide derivatization that can be synthesized rapidly and efficiently