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目的:探讨体外受精一胚胎移植(IVF—ET)的临床治疗效果。方法:对101例不孕夫妇进行106周期IVF—ET治疗的资料进行回顾性分析。结果:IVF—ET的开始周期为106个,因反应不良而取消16个周期,取消率为17.78％,最后移植90周期。90个移植周期共回收卵子数842个,每周期取卵9.36±4.52个,受精601个,受精率71.34％。卵裂584个,卵裂率97.17％。优胚262个,优质胚胎率44.86％。90周期共移植胚胎351个。平均每周期移植胚胎3.94±1.14个。临床妊娠28例,每移植周期临床妊娠率为31.11％。其中宫内妊娠26例,宫外妊娠2例,宫外孕发生率为7.14％。多胎12例,2例4胎,3例3胎,5例双胎,多胎率为42.85％。流产2例,流产率7.69％(2/26)。现有11例分娩,共15个试管婴儿出生。女性年龄是影响IVF—ET的重要因素。结论:IVF—ET是治疗女性不孕的有效方法。
Objective: To investigate the clinical effect of in vitro fertilization and embryo transfer (IVF-ET). Methods: The data of 106 cycles of IVF-ET in 101 infertile couples were analyzed retrospectively. Results: The initial cycle of IVF-ET was 106, with 16 cycles canceled due to poor response, with a cancellation rate of 17.78% and finally 90 cycles of transplantation. A total of 842 eggs were retrieved from 90 transplant cycles, with 9.36 ± 4.52 eggs per cycle, 601 fertilized and 71.34% fertilization rate. Cleavage 584, cleavage rate 97.17%. 262 excellent embryos and 44.86% high-quality embryos. A total of 351 embryos were transferred in 90 cycles. The average number of embryos transferred per week was 3.94 ± 1.14. Clinical pregnancy in 28 cases, the clinical pregnancy rate per transplant cycle was 31.11%. 26 cases of intrauterine pregnancy, 2 cases of ectopic pregnancy, ectopic pregnancy incidence was 7.14%. 12 cases of multiple births, 2 cases of 4-births, 3 cases of 3-births, 5 cases of twins, 42.85% of multiple births. Abortion in 2 cases, abortion rate of 7.69% (2/26). There are 11 cases of childbirth, a total of 15 test-tube baby was born. Female age is an important factor affecting IVF-ET. Conclusion: IVF-ET is an effective method to treat female infertility.