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目的:比较氟罗沙星与氧氟沙星注射剂治疗尿路感染的临床疗效.方法:将80倒尿路感染病例随机分为两组,分别应用氟罗沙星(0.2～0.4g/d)和氧氟沙星(0.2～0.4g/d).结果:氟罗沙星组和氧氟沙星组的总有效率分别为85%和80%,细菌清除率分别为92.5%和87.5%,两组间无显著差异(P>0.05).不良反应发生率分别为12.5%和7.5%(P<0.05).结论:氟罗沙星注射剂治疗尿路感染用药次数少,安全性较好.疗效与氧氟沙星相当.
Objective: To compare the clinical efficacy of fleroxacin and ofloxacin injection in the treatment of urinary tract infection.Methods: Eighty urinary tract infection cases were randomly divided into two groups and treated with fleroxacin (0.2-0.4 g / d) and ofloxacin (0.2 ~ 0.4g / d) .Results: The total effective rates of fleroxacin group and ofloxacin group were 85% and 80% respectively, and the bacterial clearance rates were 92.5% and 87.5% respectively, with no significant difference between the two groups (P0.05) .The incidence of adverse reactions were 12.5% and 7.5%, respectively (P0.05) .Conclusion: Fleroxacin injection is safe and effective in the treatment of urinary tract infection, and its efficacy is similar to ofloxacin.