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目的观察临床中采用黄连素对2型糖尿病患者血糖水平的影响,分析并探讨应用此治疗方法治疗2型糖尿病的安全性和可行性。方法在该院2013年10月—2014年10月就诊且自愿选择药物治疗的2型糖尿病患者中,采用简单随机抽样随机选取患者120例,将患者并分为研究组、空白对照组和黄金对照组3组,对研究组的2型糖尿病患者应用黄连素治疗,空白对照组的患者则采取安慰剂治疗,黄金对照组采用磺脲类治疗。观察并比较3种治疗方法的降糖效果。结果研究组的降糖效果要好于空白对照组(P<0.05);研究组和黄金对照组治疗后患者餐后血糖均明显下降(P<0.05),但两组间降糖效果比较差异无统计学意义(P>0.05)。结论采用黄连素治疗2型糖尿病患者具有较好的疗效和可行性,在各医院应该得到推广和应用。
Objective To observe the effect of using berberine on blood glucose level in patients with type 2 diabetes mellitus and to analyze the safety and feasibility of using this therapy in treating type 2 diabetes mellitus. Methods A total of 120 patients with type 2 diabetes were selected randomly from the hospital from October 2013 to October 2014 and were randomly selected for drug treatment. The patients were divided into study group, blank control group and gold control group Group 3, bilirubin was administered to study subjects with type 2 diabetes mellitus, placebo was given to patients in the blank control group, and sulfonylureas were used in the gold control group. Observe and compare the hypoglycemic effects of three treatment methods. Results The hypoglycemic effect of the study group was better than that of the blank control group (P <0.05). The postprandial blood glucose of the study group and the golden control group were significantly decreased (P <0.05), but no statistical difference was found between the two groups Significance (P> 0.05). Conclusion The treatment of type 2 diabetes with berberine has good curative effect and feasibility and should be popularized and applied in various hospitals.