【摘 要】
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Traditional Chinese Medicine (TCM) has been used for more than 5000 years and has attracted more and more worldwide attention because of its significant effect in prevention and treatment of diseases.However, the genetic background, the physio-ecological
【机 构】
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Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, Chin
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Traditional Chinese Medicine (TCM) has been used for more than 5000 years and has attracted more and more worldwide attention because of its significant effect in prevention and treatment of diseases.However, the genetic background, the physio-ecological characteristics, and the molecular mechanisms of most herbs are poorly understood.The Human Genome Project opens the biological Era.Genomics triggered a revolution in system biology research and enabled people to have a deeper and comprehensive understanding of living organisms.With the development of high throughput sequencing technologies and bioinformatics, herbgenomics was put forward as a discipline to facilitate biological research of TCM [1].It aims to uncover the genetic information, find gene functions, discover regulatory networks of herbs and to elucidate their molecular mechanisms in the treatment of diseases [2].More and more biological studies were performed to examin the biology of traditional medicine including whole genome sequencing [3], adaptation [4], stress resistance [5], molecular identification [6] and evolution [7].Herbgenomics will absolutely play an important role in research on modernization and internationalization of TCM.
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