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Ki- 67是一种存在于增殖细胞核内的非组蛋白性核蛋白 ,与细胞增殖密切相关[1] 。Bcl- 2基因家族是调节细胞凋亡的重要基因家族。Bcl- 2、Bax是 Bcl- 2家族极其重要的成员。Bcl- 2基因对细胞凋亡具有明显的抑制作用 ,Bax蛋白具有对抗 Bcl- 2蛋白抑制细胞凋亡的作用 ,Bcl- 2与 Ba
Ki- 67 is a non-histone nucleoprotein present in the nucleus of proliferating cells and is closely related to cell proliferation [1]. The Bcl-2 gene family is an important gene family that regulates apoptosis. Bcl-2, Bax are extremely important members of the Bcl-2 family. Bcl-2 gene has a significant inhibitory effect on apoptosis, Bax protein has the effect of inhibiting the apoptosis of Bcl-2 protein, Bcl-2 and Ba