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白细胞介素-8(IL-8)是由多种不同细胞在肿瘤坏死因子、白细胞介素-1和脂多糖刺激下分泌的多肽细胞因子。它具有嗜中性粒细胞趋化和活化作用,因此在嗜中性细胞介导的组织损害性疾病(如成人呼吸道窘迫综合征、心肌损害和类风湿性关节炎)的病理生理中起重要作用。现已成功地采用趋化试验或酶释放法检测IL-8的生物活性。但这
Interleukin-8 (IL-8) is a polypeptide cytokine secreted by a number of different cells that are stimulated by tumor necrosis factor, interleukin-1 and lipopolysaccharide. It has neutrophil chemotaxis and activation and therefore plays an important role in the pathophysiology of neutrophil-mediated tissue-damaging diseases such as adult respiratory distress syndrome, myocardial damage and rheumatoid arthritis . The bioactivity of IL-8 has been successfully tested by chemotaxis assay or enzyme release assay. But this