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目的研究增加翻转角(FA)对提高钆塞酸二钠(Gd-EOB-DTPA)肝胆期图像对比度的价值及影响。方法对54例患者分别行FA 10°、20°及30°的Gd-EOB-DTPA肝胆期成像,对不同FA间的肝脏相对强化值(LRE)、肝-脾比值(LSR)、肝-门静脉比值(LPR)、肝实质-肝占位比值(LLR)、胆管-胰腺比值(BPR)、胆管-肝脏比值(BLR)、腹壁及腹腔脂肪抑制比(FSR)进行对比分析。结果 FA为30°时LSR、LPR、LLR、BPR、BLR值最高,但腹腔和腹壁的FSR最低,FA为20°时LRE值最高,各指标不同FA组间比较均有统计学差异(P<0.05)。组内两两比较示,FA 10°和FA 30°的LRE无统计学差异(P>0.05),其余各组组内比较均有统计学差异(P<0.05)。此外,FA越大,LSR、LPR、LLR、BPR、BLR值越高,而FSR越低。结论增加FA能增加Gd-EOB-DTPA肝胆期肝实质、肝内病灶及胆管的对比度,但同时会降低腹壁和腹腔脂肪抑制效果。
Objective To study the value and influence of increasing flip angle (FA) on enhancing the contrast of Gd-EOB-DTPA images in hepatobiliary stage. Methods Fifty-four patients underwent Gd-EOB-DTPA hepatobiliary imaging at FA 10 °, 20 ° and 30 °, respectively. The liver relative enhancement (LRE), hepatic-splenic ratio (LSR) LPR, LLR, BPR, BLR, abdominal fat and abdominal fat suppression ratio (FSR) were compared. Results The FSR of LSR, LPR, LLR, BPR and BLR were the highest at FA of 30 °, but the lowest at the abdominal and abdominal wall. The values of LRE were the highest at FA of 20 °, and there were significant differences among different FA groups (P < 0.05). There was no significant difference in the LRE between FA 10 ° and FA 30 ° (P> 0.05), and there was a significant difference between the other groups (P <0.05). In addition, the larger the FA, the higher the LSR, LPR, LLR, BPR and BLR values, and the lower the FSR. Conclusion Increasing FA can increase the contrast of hepatic parenchyma, intrahepatic lesion and bile ducts of Gd-EOB-DTPA hepatobiliary stage, but at the same time, it can reduce the abdominal fat and abdominal fat inhibitory effect.