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测量由血液至气道上皮内衬液(ELF)的蛋白梯度,以调查稳定性哮喘患者血浆蛋白渗入气道腔是否增加,及其与支气管高反应性间的关系.方法 14例不吸烟哮喘患者,年龄16～88岁,其中9例血清 IgE<240 IU/ml,对尘螨、花粉、动物皮屑、烟曲菌、鸟类羽毛、白桦粉、屋尘等变应原IgE 放射变应吸附试验(RAST)反应阴性;5例1种以上或多种变应原 IgE RAST 反应阳性或血清中IgE>240IU/ml。8名不吸烟健康者为对照,年龄25～49岁.
The protein gradient from blood to airway epithelial lining fluid (ELF) was measured in order to investigate whether there is an increase in the plasma protein infiltration into bronchial airways in patients with stable asthma and its relationship with bronchial hyperreactivity.Methods 14 non-smokers with asthma , Aged 16 to 88 years old, of which 9 cases of serum IgE <240 IU / ml, on dust mites, pollen, animal dander, Aspergillus fumigatus, bird feathers, white birch powder, housing dust and other allergens IgE radioactive adsorption RAST reaction negative; 5 patients with more than one or more allergens IgE RAST reaction-positive or serum IgE> 240IU / ml. 8 non-smokers as control, aged 25 to 49 years old.