论文部分内容阅读
目的研究并探讨血清CA125与CA153联合检测对子宫内膜癌的诊断价值。方法于2013年1月至2016年6月选取30例子宫内膜癌患者和50例子宫肌瘤患者作为此次研究对象,将其分别设置为观察组、对照组。比较两组患者的CA125、CA153水平,并以术后病理诊断作为子宫内膜癌的诊断金标准,计算CA125、CA153以及二者联合检测对子宫内膜癌的诊断敏感度、特异度、准确性。结果与对照组相比,观察组的CA125、CA153水平均明显更高(P<0.05)。与单纯CA125或CA153检测相比,CA125与CA153联合检测的诊断敏感度、特异度、准确性均明显更高(P<0.05)。结论 CA125、CA153作为子宫内膜癌的肿瘤标记物,可有效反映子宫内膜癌患者的病变情况,采用CA125、CA153联合检测可对子宫内膜癌进行准确的鉴别诊断,具有较高的诊断价值。
Objective To study and explore the diagnostic value of combined detection of serum CA125 and CA153 on endometrial cancer. Methods From January 2013 to June 2016, 30 patients with endometrial cancer and 50 patients with uterine fibroids were enrolled in this study, which were respectively set as observation group and control group. The levels of CA125 and CA153 were compared between the two groups, and the postoperative pathological diagnosis was used as the gold standard for the diagnosis of endometrial cancer. The diagnostic sensitivity, specificity and accuracy of combined detection of CA125 and CA153 for endometrial cancer were calculated . Results Compared with the control group, the levels of CA125 and CA153 in the observation group were significantly higher (P <0.05). Compared with the simple CA125 or CA153 test, the diagnostic sensitivity, specificity and accuracy of the combined detection of CA125 and CA153 were significantly higher (P <0.05). Conclusion CA125 and CA153, as tumor markers of endometrial cancer, can effectively reflect the pathological changes of endometrial cancer patients. The combined detection of CA125 and CA153 can accurately differentiate endometrial cancer with high diagnostic value .