低出生体质量与成年后的心血管疾病相关,与胎儿生长受限有关的血流动力学适应性变化对心血管的持续性影响可能是其发生的基础。该研究旨在评估孕晚期胎儿血流动力学与儿童时期的心血管预后的关系。方法:纳入妊娠妇女与其子女917人,进行前瞻性研究。在妊娠30.3(95%CI 28.8~32.3)周时,运用超声及多普勒检查测定胎儿生长和胎儿动脉及胎儿心 Low birth weight is associated with cardiovascular disease in adulthood, and the sustained effects of changes in hemodynamic fitness associated with fetal growth restriction on cardiovascular outcomes may underlie its occurrence. The aim of the study was to evaluate the relationship between fetal hemodynamics in late trimester and cardiovascular outcome in childhood. METHODS: 917 pregnant women and their children were enrolled in a prospective study. At 30.3 (95% CI 28.8-32.3) weeks of gestation, fetal growth and fetal arteries and fetal heart were measured using sonography and Doppler