脂质体作为药物载体,以其选择性高、靶向性强,从而具有减少药物剂量、降低毒性、减少副作用等许多优点而受到广泛重视。目前,脂质体的制备工艺、稳定性、临床应用及其物理化学和生理学等基础方面均已开展大量研究。其中,通透性问题由于直接关系到作为药物载体的脂 Liposomes as drug carriers, with its high selectivity, strong targeting, which has the advantages of reducing drug dosage, reducing toxicity, reducing side effects and many other advantages have received widespread attention. At present, liposome preparation technology, stability, clinical applications and its physical chemistry and physiology and other basic aspects have carried out a large number of studies. Among them, the problem of permeability is directly related to the lipid as a drug carrier