二甲基乙酰胺是一种低毒类有机溶剂,作为毒性明显的二甲基甲酰胺的替代品,广泛用于石油加工和有机合成工业中。国内二甲基乙酰胺的市场消费量日益增多,而对其毒性的认识尚不全面。作者针对其代谢过程、各系统毒作用特征及机制方面的最新研究予以综述。 Dimethylacetamide is a low toxicity organic solvent that is widely used in petroleum processing and organic synthesis industries as a substitute for virulent dimethylformamide. Domestic dimethylacetamide market consumption is increasing, but its toxicity is not yet fully understood. The author reviews the latest research on the metabolic processes, the toxicological characteristics and mechanisms of various systems.