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目的探讨孟鲁司特与酮替芬治疗小儿咳嗽变异性哮喘(CVA)的方法及临床疗效对比。方法将2010年2月-2012年11月泌阳县人民医院收治的84例CVA患儿随机分为对照组及观察组,除常规治疗外,对照组给予酮替芬治疗,观察组给予孟鲁司特治疗,记录并作回顾性分析。结果观察组总有效率大于对照组,治疗后两组患儿日间及夜间症状评分低于治疗前,且差异均有统计学意义(P<0.05)。结论与酮替芬相比,孟鲁司特治疗小儿CVA临床疗效更优,值得推广应用。
Objective To investigate the clinical efficacy of montelukast and ketotifen in the treatment of children with cough variant asthma (CVA). Methods Eighty-two CVA children admitted to Biyang County People’s Hospital from February 2010 to November 2012 were randomly divided into control group and observation group. In addition to conventional treatment, the control group was treated with ketotifen. The observation group was given Menglu Stent treatment, record and retrospective analysis. Results The total effective rate of the observation group was higher than that of the control group. The scores of daytime and nighttime symptom scores of the two groups after treatment were lower than those before treatment, and the differences were statistically significant (P <0.05). Conclusion Compared with ketotifen, montelukast treatment of children with CVA clinical efficacy is better, it is worth promoting the application.