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右旋糖酐40葡萄糖注射液(500 ml)的成分为30 g右旋糖酐40与25 g葡萄糖。右旋糖酐40为多糖混合物,主要类型为α-1,6-葡萄糖,由右旋糖酐经水解和分馏获得,为葡萄糖聚合物。在临床应用非常广泛,主要适用于血管栓塞性疾病及休克,具有改善微循环和扩充血容量的双重作用。由于相对分子质量小,在体内停留时间短,易从尿中排出,因此扩充血容量的作用时间短暂,约3 h,但具有渗透性利尿作用,能附着于红细胞、血小板表面,使已经聚集的红细胞和血小板解聚,降低血液黏滞性,从而改善微循环,预防血栓形
The dextran 40 glucose injection (500 ml) has a composition of 30 g dextran 40 and 25 g glucose. Dextran 40 is a mixture of polysaccharides, mainly of the type α-1,6-dextrose, obtained from hydrolysis and fractionation of dextran, which is a glucose polymer. In a wide range of clinical applications, mainly for vascular embolic disease and shock, with the improvement of microcirculation and the expansion of blood volume dual role. Due to the small relative molecular mass, short residence time in the body, easy to excreted from the urine, so the role of expansion of blood volume transient time, about 3 h, but with osmotic diuretic effect, can be attached to the red blood cells, platelet surface, Red blood cells and platelets depolymerization, reducing blood viscosity, thereby improving microcirculation, prevention of thrombosis