人类疱疹病毒8型(Human herpesvirus-8,HHV-8)又名Kaposi肉瘤相关疱疹病毒(Kaposi’s sarcoma-associated herpesvirus,KSHV),属Rhadino病毒或者γ-2疱疹病毒,与γ-1疱疹病毒、EB病毒(EBV)同属人类γ疱疹病毒,是由Chang等在1994年采用代表性差异分析法从一例AIDS-KS患者的病变组织中发现的一种新病毒。随着对HHV-8及其亚型的深入研究,其与非KS肿瘤的关系也逐渐引起了各国学者的关注。近年来大量研究表明其与非KS肿瘤疾病的关系密切。 Human herpesvirus-8 (HHV-8), also known as Kaposi’s sarcoma-associated herpesvirus (KSHV), belongs to the genus Rhadino or γ-2 herpesvirus and is associated with γ-1 herpesvirus, EB The virus (EBV) belongs to the human gamma herpesvirus and was a novel virus discovered by Chang et al. In 1994 using representative differential assays from diseased tissue in an AIDS-KS patient. With the in-depth study of HHV-8 and its subtypes, its relationship with non-KS tumors has gradually attracted the attention of scholars from all over the world. In recent years, a large number of studies have shown that it is closely related to non-KS tumor diseases.