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目的:观察甘利欣注射液联合硫普罗宁治疗中暑引起肝损害的疗效。方法:将46例中暑伴有肝损害的患者随机分成两组,硫普罗宁组(A组)和甘利欣注射液联合硫普罗宁组(B组),观察治疗前后患者临床症状改善情况及总胆红素、血清谷丙转氨酶、血清谷草转氨酶等指标的变化。结果:应用甘利欣注射液联合硫普罗宁治疗中暑引起的肝损害总有效率为87.0%,硫普罗宁组总有效率为60.9%,两组患者总有效率差异有显著性(P<0.05)。结论:甘利欣注射液联合硫普罗宁治疗中暑引起的肝损害,临床上具有较好的疗效。
Objective: To observe the curative effect of GanLiXin injection combined with tiopronin on liver damage induced by heat stroke. Methods: Forty-six patients with liver stroke accompanied by heat stroke were randomly divided into two groups. Patients in the group treated with tiopronin (group A) and GanLiXin injection combined with tiopronin (group B) were observed before and after treatment to improve the clinical symptoms and the total Bilirubin, serum alanine aminotransferase, serum aspartate aminotransferase and other indicators of change. Results: The total effective rate of liver injury caused by heat stroke was 87.0% and the total effective rate of tiopronin was 60.9%. The total effective rate was significantly different between the two groups (P0.05) . Conclusion: Ganlixin injection combined with tiopronin in the treatment of liver damage caused by heat stroke, has a good clinical efficacy.