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目的观察金水宝联合缬沙坦治疗蛋白尿和慢性肾功不全的临床疗效。方法30例患者做自身前后对照。对照组单用缬沙坦,治疗组用金水宝联合缬沙坦。两组同时用西医常规治疗,包括饮食疗法(优质低蛋白、高热量、低磷),纠正酸中毒、水电解质紊乱,降压、抗凝治疗及控制感染。疗程均为3个月。结果治疗组尿白蛋白减少总有效率是88.33%,血肌酐减少总有效率是47.35%,血肌酐减少较对照组差异(P<0.05)有显著性;尿白蛋白减少较对照组差异(P<0.01)有极显著性。结论金水宝联合缬沙坦治疗蛋白尿和慢性肾功不全的临床疗效显著,是理想用药。
Objective To observe the clinical efficacy of Jinshuibao combined with valsartan in the treatment of proteinuria and chronic renal insufficiency. Methods Thirty patients underwent self-control. Valsartan alone in the control group, the treatment group with gold Shui Po joint valsartan. Both groups were treated routinely with western medicine, including diet therapy (high-quality low-protein, high-calorie, low-phosphorus), correct acidosis, water and electrolyte disorders, blood pressure, anticoagulant therapy and infection control. Treatment are 3 months. Results In the treatment group, the total effective rate of reducing urinary albumin was 88.33%, the total effective rate of reducing serum creatinine was 47.35%, and the decrease of serum creatinine was significant (P <0.05); the difference of urinary albumin was lower than that of the control group (P <0.01) is extremely significant. Conclusion The clinical efficacy of Jinshuibao combined with valsartan in the treatment of proteinuria and chronic renal insufficiency is significant and is an ideal medication.