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早在1942年Alden就发现大鼠排卵后切除卵巢,并不影响卵的运输,从而提出大鼠卵运输是不受排卵后卵巢激素分泌的影响。然而,至今在小鼠身上并无类似报导。有人设想,输卵管肌肉活动促进卵子的运输,是受排卵前卵巢分泌的孕酮所控制,而不受排卵后卵巢分泌的激素所影响。本文试图在小鼠身上用抗孕酮甾体证明这种假设。于小鼠妊娠的第1天切除卵巢,并不影响卵的运输,如于动情前期的当天给予孕酮,胚泡转运明显加快。如在妊娠的第1,2,3天给予抗孕激素的甾体-RMI_(12936),胚泡在生殖道内的位置和对照组相比明显延迟,说明该激素阻止胚泡的转运。作者
As early as 1942 Alden found ovariectomized ovariectomized rats did not affect the transport of eggs, suggesting that rat egg transport is not affected by ovulation after ovarian hormone secretion. However, so far no similar reports have been reported in mice. Some people think that tubal muscle activity to promote the transport of eggs, ovulation by the progesterone is controlled by the ovulation, but not by ovarian hormone secretion after ovulation. This article attempts to prove this hypothesis with anti-progesterone steroids in mice. Excision of ovaries on the first day of pregnancy in mice did not affect the transport of eggs. Progesterone was administered on the day of early estrus and the blastocyst transit was significantly accelerated. For example, in the first and second trimester of pregnancy, anti-progesterone steroid-RMI_ (12936) was given a significantly delayed position in the genital tract compared with the control group, indicating that the hormone prevents blastocyst transport. Author