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2-巯基吡啶氧化物为一外用抗菌药。我们发现其在低浓度时对体外培养的多种人体肿瘤细胞株有很强的杀灭作用,但对动物移植性肿瘤实验治疗无效。试验表明其体内血药半衰期短和生物转化快。为此,我们设
Pyrithione is an external antimicrobial. We found that it has a strong killing effect on a variety of human tumor cell lines cultured in vitro at low concentration, but it is not effective in the experimental treatment of animal transplanted tumors. Test shows that the blood half-life in vivo short and rapid biological conversion. To this end, we set