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目的:评价骶前-腰大肌后间隙阻滞联合选择性腰神经根阻滞用于全麻膝下骨折手术患者的改良效果。方法:择期全麻下行膝下骨折手术患者46例，ASA分级Ⅰ或Ⅱ级，年龄22～64岁，BMI0.05)；与C组比较，S组术中瑞芬太尼和舒芬太尼用量、术后24 h内和48 h内舒芬太尼和氟比洛芬酯用量降低，麻醉苏醒时间、气管拔管时间、术后首次肠道排气时间和术后住院时间缩短，术后恶心和呕吐发生率降低(n P<0.05)。n 结论:相对于单纯全身麻醉而言，骶前-腰大肌后间隙阻滞联合选择性腰神经根阻滞用于全麻膝下骨折手术患者，可减少阿片类药物用量，抑制术后痛敏反应，促进术后早期恢复。“,”Objective:To evaluate the improved efficacy of anterior sacral-posterior psoas major space block combined with selective lumbar nerve root block in the patients undergoing surgery for fracture below the knee with general anesthesia.Methods:Forty-six American Society of Anesthesiologists physical status Ⅰ or Ⅱpatients, aged 22-64 yr, with body mass index 0.05). Compared with group C, the consumption of intraoperative remifentanil and sufentanil during operation and sufentanil and flurbiprofen axetil within 24 and 48 h after operation was significantly decreased, the time of emergency from anesthesia, extubation time, time to first intestinal exhaust, and postoperative length of hospital stay were shortened, and the incidence of postoperative nausea and vomiting was decreased in group S (n P<0.05).n Conclusion:Compared with general anesthesia alone, anterior sacral-posterior psoas major space block combined with selective lumbar nerve root block can reduce the consumption of opioids, inhibit postoperative hyperalgesia, and promote early recovery after surgery when used for the patients undergoing surgery for fracture below the knee with general anesthesia.