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苏联的先进医学家以巴甫洛夫的高级神经活动学说和维金斯基的兴奋与阻抑及传导暂停学说为基础,进一步发挥了结核菌素在临床诊断上的作用,建立了结核菌素的分级和定度诊断法。分级试验是采用各种浓度的结核菌素(100％,25％ ,5％,1％)溶液作披耳凯氏试验;定度试验是利用小剂量结核菌素稀释液作孟都氏试验。如敏感性增高可以说明有活动或恶化的结核病;反之,对结核菌素的稳定性增高,则为病变趋向静息的现象。结核病患者的敏感性与神经系统诸位相的移行,基本上是与结核菌素在皮肤上的反应一致的。
Based on Pavlov’s advanced theory of neural activity and Viginsky’s excitement and repression and conduction suspension doctrine, advanced Soviet physicians further played the role of tuberculin in clinical diagnosis. Grading and diagnostic methods. Grading tests were conducted using various concentrations of tuberculin (100%, 25%, 5%, 1%) solution for the Kupffer’s Kjeldahl test; calibration test is the use of low doses of tuberculin dilution for Mendel’s test. Such as increased sensitivity may indicate activity or deterioration of tuberculosis; conversely, the increased stability of tuberculin, the lesions tend to rest phenomenon. The sensitivity of tuberculosis patients and the phase transition of the nervous system is basically consistent with the reaction of tuberculin in the skin.