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硝酸甘油的口腔内喷雾给药法有多种优点:给药方便,吸收迅速,有效期长达三年。硝酸甘油喷雾剂的疗效和价格与硝酸甘油片剂差不多。 常见的硝酸甘油制剂有片剂、胶囊、软膏、纸片型、溶液及贴剂等。对目前应用的剂型感到不满意的患者可使用这种新型喷雾剂,每喷雾一次给药0.4mg 硝酸甘油片容易挥发,经相当一段时间后药效减弱。保存与喷雾器内的硝酸甘油效力可保持三年,保证每次喷雾给药有效。由于雾状药物可经舌下及其周围组织迅速吸收而进入血流,心绞痛立即缓解。
Nitroglycerin oral spray administration has many advantages: easy administration, rapid absorption, valid for up to three years. The efficacy and price of nitroglycerin spray is similar to nitroglycerin tablets. Common nitroglycerin preparations are tablets, capsules, ointment, paper type, solution and patch. Patients who are dissatisfied with the current dosage form can use this new type of spray, which is readily volatile with 0.4 mg of nitroglycerin once per spray, with a diminished efficacy over a period of time. The effectiveness of preserving and nitroglycerin in the nebulizer can be maintained for three years, ensuring that each spray is administered effectively. As the hazy drugs can be quickly absorbed through the tongue and its surrounding tissue and into the bloodstream, angina relief immediately.