炎症的促凝作用以及凝血-炎症网络的相互作用所致的恶性循环,已成为血栓形成的重要发病机制。长期以来凝血系统局限在止血机制与血栓形成中的研究,炎症局部在创伤与感染病理过程中的探讨。近几年大量实验与临床研究表明凝血与炎症之间存在网络关系[1]。1凝血酶的促炎作用凝血酶 The pro-coagulant effect of inflammation and the vicious circle caused by the interaction of coagulation-inflammation network have become important pathogenesis of thrombosis. For a long time the coagulation system is confined to the hemostatic mechanism and thrombosis, and the inflammation in the trauma and infection pathological process. In recent years, a large number of experimental and clinical studies have shown that there is a network between coagulation and inflammation [1]. 1 thrombin pro-inflammatory role of thrombin