用放射性同位素标记的单克隆抗体(McAb),利用抗原、抗体的免疫特异性结合,以McAb作为定向导航的载体,可用于肿瘤进行诊断和治疗。 用精制的hCG多次免疫的BALB/C小鼠的脾细胞与骨髓瘤细胞(NS-1)融合,筛选,克隆化,得多株抗hCG-β的McAb细胞株。取2B_5和2D_8二个阳性细胞株,诱发腹水,把从腹水中提纯的IgG供标记 With radioisotope-labeled monoclonal antibodies (McAbs), immunospecific binding of antigens, antibodies, and McAb as vectors for directional navigation can be used for the diagnosis and treatment of tumors. Splenocytes from BALB/C mice that were repeatedly immunized with purified hCG were fused with myeloma cells (NS-1), screened, cloned, and multi-stranded anti-hCG-β McAb cell lines. Two positive cell lines, 2B_5 and 2D_8, were used to induce ascites, and IgG purified from ascites was labeled.