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[目的]了解西宁地区乙型病毒性肝炎流行现状。[方法]采用多阶段整群随机抽样的方法,对西宁市1～60岁以上各年龄组的自然人群,每个年龄段随机抽取200人,共2125人进行乙肝病毒感染血清学检测。[结果]西宁地区调查人群HBsAg阳性率、抗HBc阳性率、抗HBs阳性率分别为4.56%、19.36%、29.75%;1~14岁儿童HBsAg阳性率为1.74%,15岁以上人群HBsAg阳性率为5.61%;农村HBsAg阳性率高于城区;藏族HbsAg阳性率高于汉族等民族;农民、工人的HBsAg阳性率明显高于其他职业。[结论]加强新生儿(尤其是少数民族农村地区)乙肝疫苗免疫接种依然是今后乙肝疫苗预防工作的重点。
[Objective] To understand the prevalence of hepatitis B in Xining area. [Methods] A multistage cluster random sampling method was used in this study. A total of 2125 people were randomly selected from each age group of 1 to 60 years old in Xining City for serological detection of hepatitis B virus infection. [Results] The positive rates of HBsAg, anti-HBc and anti-HBs in the surveyed population in Xining were 4.56%, 19.36% and 29.75% respectively; the positive rate of HBsAg in children aged 1-14 was 1.74%; the positive rate of HBsAg in children over 15 years Was 5.61%. The positive rate of HBsAg in rural areas was higher than that in urban areas. The positive rate of HbsAg in Tibetan was higher than that of Han nationality. The positive rate of HBsAg among peasants and workers was significantly higher than that of other occupations. [Conclusion] Strengthening hepatitis B vaccine immunization of newborns (especially minority rural areas) remains the focus of hepatitis B vaccine prevention in the future.