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遗传因素可能影响结核病敏感性,但控制敏感性特殊基因尚未鉴定。鼠对一些分支杆菌有自然抗感染力是受与巨噬细胞蛋白1(Nrampl)有关自然抗感染基因影响,但人此基因同系物NRAMP1对结核病人作用不清楚。本文在西非冈比亚病例对照研究结核病中对NRAMP1基因
Genetic factors may affect tuberculosis susceptibility, but specific genes that control sensitivity have not been identified. The natural resistance of mice to some mycobacteria is affected by the natural anti-infective genes associated with Nrampl, but the role of the human cognate NRAMP1 in tuberculosis is unclear. This article examines the NRAMP1 gene in tuberculosis in the Gambia West Africa case-control study