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早在70年代初期,就有许多人提出急性淋巴细胞白血病(ALL)有完全治愈的可能。近年来,由于化学治疗方案的改进,新的抗白血病药物不断出现。以及在骨髓移植和单克隆抗体研究方面取得的令人嘱目的进展,ALL的完全缓解率已达70～90%,本人就近年来ALL的治疗进展作如下综述。常规治疗方面一、诱导缓解临床治疗ALL的早期贡献之一在于阐明了必须要先使病情完全缓解,才能延长病人的存活时间。儿童ALL,Free报导联合用药治疗会使更多病人完全缓解。完全缓解率越高,患者存活期越长,诱导缓解越早,其预后越好。Sallan用
As early as the early 1970s, many people proposed the possibility of complete cure for acute lymphoblastic leukemia (ALL). In recent years, due to the improvement of chemotherapy, new anti-leukemia drugs continue to appear. As well as the progress made in the research of bone marrow transplantation and monoclonal antibody, the complete remission rate of ALL has reached 70-90%. I will summarize the progress of ALL in recent years. Conventional treatment First, the induction of remission clinical treatment One of the early contributions of ALL is to clarify the need to fully alleviate the condition before they can extend the patient’s survival time. Children ALL, Free reported that combination therapy could completely relieve more patients. The higher the complete remission rate, the longer the patient’s survival, the earlier the induction of remission, the better the prognosis. Sallan used