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目的回顾性调查某综合性三甲医院住院患者注射用质子泵抑制剂超说明书用药情况。方法统计2014年住院患者使用注射用质子泵抑制剂的用药医嘱,按照药品说明书规定的内容,分析是否存在超说明书用药,统计超说明书用药的类型。结果共抽样分析用药医嘱3 271条,30个科室(共34个)存在超说明书用药情况,总发生率为90.74%,类型以超适应症为主。其中注射用兰索拉唑、注射用埃索美拉唑、注射用奥美拉唑、注射用泮托拉唑、注射用奥美拉唑超说明书用药发生率分别为98.72%,99.30%,10.67%,94.91%,100%。结论注射用质子泵抑制剂在该院被普遍使用,超说明书用药情况较为突出,应通过管控措施规范超说明书用药行为,促进临床合理用药。
Objective To retrospectively investigate the use of superior instructions of proton pump inhibitor for inpatients in a comprehensive top three hospital. Methods Statistics 2014 hospitalized patients using proton pump inhibitor for medical advice, in accordance with the provisions of the drug specification, analysis of the existence of super manual medication, statistical super manual medication type. Results A total of 3 271 medical prescriptions were analyzed by sampling, and 30 cases (34 cases in all) were surgically treated. The total incidence rate was 90.74%. The main types were super-indications. Including lansoprazole for injection, esomeprazole for injection, omeprazole for injection, pantoprazole for injection, omeprazole for injection super-instructions for the incidence of drug were 98.72%, 99.30%, 10.67 %, 94.91%, 100%. Conclusion Proton pump inhibitors for injection are commonly used in this hospital. The instructions for using drugs in super manuals are more conspicuous. Control measures should be taken to regulate the usage of drugs and to promote rational drug use in clinical practice.