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目的探讨动脉粥样硬化性脑梗塞患者血清胆红素和血脂的相关性。方法选择我院2011年1月-2012年5月收治的65例动脉粥样硬化性脑梗塞患者作为观察组,同期健康体检者68例作为对照组,观察动脉粥样硬化性脑梗塞患者的血清胆红素及血脂水平,分析患者血清胆红素和血脂的相关性。结果观察组血清总胆红素(TBI)、高密度脂蛋白胆固醇(HDL-C)均明显低于对照组,而血清胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)均明显高于对照组,组间差异均有统计学意义(P<0.05);血清胆红素与低TC、TG、LDL-C呈负相关,与HDL-C呈正相关。结论动脉粥样硬化性脑梗塞患者血清TBI和血脂具有相关性,低水平胆红素及高水平低密度脂蛋白胆固醇是发生疾病的危险信号,应当引起临床关注。
Objective To investigate the correlation between serum bilirubin and blood lipids in patients with atherosclerotic cerebral infarction. Methods Sixty-five patients with atherosclerotic cerebral infarction admitted from January 2011 to May 2012 in our hospital were selected as the observation group and 68 healthy subjects were taken as the control group during the same period. The serum of patients with atherosclerotic cerebral infarction Bilirubin and blood lipid levels, analysis of the correlation between serum bilirubin and lipids. Results The levels of serum total bilirubin (TBI) and high density lipoprotein cholesterol (HDL-C) in the observation group were significantly lower than those in the control group. However, serum cholesterol, triglyceride, low density lipoprotein cholesterol C) were significantly higher than those in the control group (P <0.05). Serum bilirubin was negatively correlated with low TC, TG and LDL-C and positively correlated with HDL-C. Conclusion Serum TBI is associated with serum lipids in patients with atherosclerotic cerebral infarction. Low level of bilirubin and high level of low-density lipoprotein cholesterol are the risk signals for the occurrence of the disease and should be of clinical concern.