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目的:研究冠心病不稳定性心绞痛患者血清尿酸,C-反应蛋白,肌钙蛋白—T水平并与对照组比较,探讨血清尿酸,C-反应蛋白,肌钙蛋白-T是否为不稳定性心绞痛的危险因子。方法:对明确诊断的50名不稳定性心绞痛患者及62名稳定性心绞痛患者进行研究,测定血清尿酸,C-反应蛋白,肌钙蛋白-T的水平,并进行相关的统计学分析。结果;不稳定性心绞痛组血清尿酸,C-反应蛋白,肌钙蛋白-T的水平分别为[(395.290±76.1742)umol/L,(12.838+16.775)mg/L,(0.207+0.339)ms/L]明显高于稳定性心绞痛组[(303.41+50.132)umol/L,(2.951+1.664)mg/L,(0.052+0.009)]ms/L,P<0.01],不稳定性心绞痛患者血清尿酸与C-反应蛋白呈正相关(r=0.313,P<0.01)。血清尿酸水平与肌钙蛋白-T也呈正相关(r=0.376,P<0.01)。结论:不稳定性心绞痛患者血清尿酸,C-反应蛋白及肌钙蛋白-T浓度明显升高,血清尿酸,C-反应蛋白,肌钙蛋白-T或许可作为不稳定性心绞痛的危险因子。
Objective: To investigate the levels of serum uric acid, C-reactive protein and troponin-T in patients with coronary heart disease and to compare the levels of serum uric acid, C-reactive protein and troponin-T in patients with unstable angina Risk factors. Methods: Fifty patients with unstable angina pectoris and 62 patients with stable angina pectoris diagnosed were studied. The levels of serum uric acid, C-reactive protein and troponin-T were measured and correlated with statistical analysis. Results The levels of serum uric acid, C-reactive protein and troponin-T in patients with unstable angina were (395.290 ± 76.1742) umol / L, (12.838 ± 16.775) mg / L, L was significantly higher than that in patients with stable angina [(303.41 + 50.132) umol / L, (2.951 + 1.664) mg / L, (0.052 + 0.009) ms / L, P <0.01] And C-reactive protein was positively correlated (r = 0.313, P <0.01). Serum uric acid levels were also positively correlated with troponin-T (r = 0.376, P <0.01). CONCLUSIONS: Serum uric acid, C-reactive protein and troponin-T levels are significantly elevated in patients with unstable angina and serum uric acid, C-reactive protein and troponin-T may be considered as risk factors for unstable angina.