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病情严重时甲状腺激素水平出现异常,通常称作“正常甲状腺病态综合征”(cuthyroid sick syndrome),表现为血清T_4和T_3水平降低而rT_3水平增高。心脏骤停既可能极度刺激甲状腺激素的释出,又可能加重“正常甲状腺病态综合征”,试析如下。 A组34～83(中位数69)岁的24(男10、女14)例患者曾在监护病房内发生心啶骤停,立即开始复苏治疗,7例存活。复苏当时和随后10min各采血标本一次。无一例使用过糖皮质激素。该组基础疾病为:心血管疾病10例,癌肿和腋毒性休克各3例,脑血管意外和慢性阻塞性肺病各2例,药物过量(肺水肿)、破伤风和终末期肾病各1例(共23例,原文如此)。B组22例患者在监护病房内未发生过心脏骤停。 A组各项甲状腺功能指标异常较B组更常见且更明显。AB两组内:T_3水平低于正常分别占
Thyroid hormone levels are abnormal in a serious condition and are often referred to as “cuthyroid sick syndrome” and appear to be a decrease in serum T_4 and T_3 levels and an increase in rT_3 levels. Cardiac arrest may both be extremely stimulating the release of thyroid hormone, but also may aggravate “normal thyroid sick syndrome”, try below. In Group A, 24 (male 10, female 14) patients aged 34 to 83 (median 69) had a cardiac arrest in an ICU, resuscitation was initiated immediately, and 7 survived. Resuscitation then and 10min each blood specimen once. No one used glucocorticoid. The group of underlying diseases were: cardiovascular disease in 10 cases, cancer and axillary shock in 3 cases, cerebrovascular accident and chronic obstructive pulmonary disease in 2 cases, drug overdose (pulmonary edema), tetanus and end-stage renal disease in 1 case (A total of 23 cases, the original text so). Twenty-two patients in group B had no cardiac arrest in the ICU. A group of thyroid function abnormalities than the B group more common and more obvious. AB two groups: T_3 levels were lower than normal accounted for