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目的 分析肝动脉介入治疗加 (减 )全身化疗治疗转移性肝癌。方法 对 16 4例转移性肝癌进行回顾性研究 , 组 10 0例 ,采用肝动脉介入治疗加 (减 )全身化疗 ; 组 6 4例 ,采用单纯静脉化疗 ,观察两组疗效、生存情况 ,并进行统计分析对比。结果 组 CR2 6 .0 % ,PR5 8.0 % ,有效率 84.0 % ; 组 CR6 .3% ,PR18.8% ,有效率2 5 .0 % , 组疗效显著高于 组 (P<0 .0 1)。生存率 1～ 5年 组分别为 85 .6 %、42 .6 %、2 6 .4%、3.6 %、2 .4% ; 组分别为 2 6 .0 %、15 .0 %、8.0 % ,4～ 5年生存率均为 0。 组生存率显著高于 组 (P<0 .0 1)。结论 肝动脉介入治疗加 (减 )全身化疗是非手术治疗转移性肝癌较为有效的方法。
Objective To analyze the interventional treatment of hepatic artery plus (or minus) systemic chemotherapy for metastatic liver cancer. Methods A retrospective study of 164 patients with metastatic liver cancer was performed. One hundred patients were treated with hepatic artery intervention plus or minus systemic chemotherapy. Sixty-four patients were treated with simple intravenous chemotherapy. The efficacy and survival of the two groups were observed. Statistical analysis and comparison. Results CR2 6.0 %, PR5 8.0 %, effective rate 84.0 %; group CR6 .3%, PR18.8%, effective rate 25.0 %, group efficacy was significantly higher than the group (P <0 1) . The survival rate in the 1 to 5 year group was 85.6%, 42.6%, 26.4%, 3.6%, and 2.4%, respectively; the group was 26.0%, 15.0%, 8.0%, respectively. The 4 to 5 year survival rate is 0. The group survival rate was significantly higher than the group (P<0.01). Conclusion Interventional hepatic artery intervention plus (or minus) systemic chemotherapy is a more effective method for non-surgical treatment of metastatic liver cancer.