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目的:探讨重复经颅磁刺激(rTMS)配合个性化护理对抑郁症患者负性情绪及生活质量的影响。方法:将83例抑郁症患者按照家庭分型标准分为:极端型、中间型以及平衡型3组,探讨3组患者的临床疗效、负性情绪以及生活质量。结果:平衡型、中间型总有效率显著高于极端型(χ~2=8.34,7.64;P<0.05)。治疗后各分型组汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)、简易应付方式问卷(SCSQ)、焦虑自评量表(SAS)、抑郁自评量表(SDS)评分均降低,与治疗前比较差异有统计学意义(t=5.89~9.23,P<0.05),而世界卫生组织生活质量测定量表简表(WHOQOL-BREF)中生理领域、心理领域及社会关系领域方面评分均显著高于治疗前(t=6.22~8.17,P<0.05)。治疗后,中间型、平衡型组HAMA、HAMD、SCSQ评分均显著低于极端型组(t=4.36~6.48,P<0.05)。治疗6周后,中间型组SAS、SDS评分显著低于极端型(t=6.87,7.99;P<0.05),WHOQOL-BREF量表中生理领域、心理领域及社会关系领域评分均显著高于平衡型、极端型组(t=4.39~7.44,P<0.05)。结论:rTMS联合个性化护理对中间型、平衡型抑郁症患者的治疗效果及负性情绪、生活质量评分显著优于极端型。
Objective: To investigate the effect of rTMS combined with personalized nursing on the negative emotions and quality of life in patients with depression. Methods: Eighty-three depression patients were divided into three groups: extreme type, intermediate type and balanced type. The clinical efficacy, negative emotions and quality of life in three groups were studied. Results: The total effective rate of balanced type and intermediate type was significantly higher than that of extreme type (χ ~ 2 = 8.34, 7.64; P <0.05). After treatment, HAMA, HAMD, SCSQ, SAS and SDS were decreased in all subgroups of patients after treatment. (T = 5.89 ~ 9.23, P <0.05), while the WHOQOL-BREF scores in the field of physiology, psychology and social relations Were significantly higher than before treatment (t = 6.22 ~ 8.17, P <0.05). After treatment, the scores of HAMA, HAMD and SCSQ in middle and balanced group were significantly lower than those in extreme group (t = 4.36 ~ 6.48, P <0.05). After six weeks of treatment, SAS, SDS scores of intermediate type group were significantly lower than those of extreme type (t = 6.87, 7.99; P <0.05). The score of WHOQOL-BREF in physiology, psychology and social relations were significantly higher than the balance Type, extreme type group (t = 4.39 ~ 7.44, P <0.05). CONCLUSION: The therapeutic effect and negative emotion of rTMS combined with personalized care on patients with moderate and balanced depression are significantly better than the extreme type in quality of life score.