患者,男性,48岁,1976年右下腹部痛,发现咖啡色尿。1979年海姆试验糖水试验阳性,诊断为阵发性睡眠性血红蛋白尿(PNH),此后给予氟羟甲基睾丸素及强地松龙治疗。1984年1月27日,溶血发作后,少尿入院。因尿素氮89mg/dl,肌酐8.0mg/dl,乳酸脱氢酶4891单位升,考虑 PNH 溶血发作后并发急性肾功能不全,进行血液透析,输洗涤红细胞而得恢复。肾组织活检,在肾小管内有含铁 The patient, male, 48 years old, had a right lower quadrant pain in 1976 and found brown urine. 1979 Hem test sugar water test was positive, diagnosed as paroxysmal nocturnal hemoglobinuria (PNH), since then given fluoromormin testosterone and prednisolone treatment. January 27, 1984, hemolysis episodes, oliguria admitted to hospital. Due to urea nitrogen 89mg / dl, creatinine 8.0mg / dl, lactate dehydrogenase 4891 units liter, consider the onset of PNH hemolysis complicated by acute renal insufficiency, hemodialysis, transfusion of washed red blood cells recovered. Kidney biopsy, there is iron in the tubules