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目的探讨反流性食管炎与幽门螺杆菌(Helicobacter pylori,Hp)感染的关系。方法 70例经胃镜检查确诊为胃-食管反流病患者为观察组,同期90例胃镜检查诊断为轻度慢性胃炎者为对照组,2组均行14 C呼气试验及快速尿素酶法检测Hp,比较其结果。结果观察组Hp感染率31.4%,对照组54.4%,2组比较差异有统计学意义(P<0.05)。结论反流性食管炎患者Hp感染率较低,Hp可能对反流性食管炎具有保护作用。
Objective To investigate the relationship between reflux esophagitis and Helicobacter pylori (Hp) infection. Methods Seventy patients diagnosed as Gastroesophageal Reflux Disease by gastroscopy were selected as the observation group. Ninety patients with mild chronic gastritis underwent gastroscopy at the same period were selected as the control group. The 14 C breath test and rapid urease test Hp, compare the results. Results The Hp infection rate in observation group was 31.4% and in control group was 54.4%. There was significant difference between two groups (P <0.05). Conclusions Reflux esophagitis in patients with Hp infection rate is low, Hp may have a protective effect on reflux esophagitis.