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对老年及老年前期无糖尿病的65例高血压患者和54例正常血压人的空腹血糖(BG)、胰岛素(IS)和胰高血糖素(GC)的浓度进行测定。结果显示,高血压组和正常血压组的BG、IS、 及GC均无显著差异(均r>0.05)。按是否肥胖进一步分组分析,发现在非肥胖者中,高血压组的 值明显小于正常血压组(P<0.05)。提示,无糖尿病的老年前期及老年高血压患者,总体上看不存在明显的高胰岛素血症和胰岛素抵抗,但在高血压患者中的非肥胖者显示胰岛素敏感性降低的倾向。
The levels of fasting blood glucose (BG), insulin (IS) and glucagon (GC) were measured in 65 elderly hypertensive patients without prehypertension and 54 normotensive subjects. The results showed no significant difference in BG, IS, and GC between hypertensive and normotensive subjects (all r> 0.05). According to whether obesity further subgroup analysis found that in non-obese, the value of hypertension group was significantly less than the normal blood pressure group (P <0.05). Prompted that in elderly patients with prehypertensive and elderly hypertension without diabetes, there is generally no apparent hyperinsulinemia and insulin resistance, but non-obesity in hypertensive patients tends to show reduced insulin sensitivity.