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机体对抗肿瘤的免疫反应以细胞免疫为主,并以T 细胞为主要效应细胞。巨噬细胞为细胞免疫的一部分,已往研究多限于动物实验。1976年中国医学科学院肿瘤防治研究所首先报道用斑蝥酊刺激患者皮肤产生皮疱,从疱液中获得大量巨噬细胞,用以测定其吞噬功能,发现在恶性肿瘤患者中,吞噬功能明显下降。1979年11月至1980年6月我们对妇科恶性肿瘤患者34例作了巨噬细胞吞噬功能检测,以妇科良性肿瘤39例及非肿瘤患者30例作为对照。此外,对部分术后病例作了试验,与术前
The body’s immune response against tumors is mainly cellular immunity, and T cells as the main effector cells. Macrophages as part of cellular immunity, the previous study mostly limited to animal experiments. Cancer Institute of Chinese Academy of Medical Sciences in 1976 first reported that the skin with cantharidin tincture to stimulate the skin of patients with blisters, blisters fluid obtained from a large number of macrophages to detect its phagocytic function found in patients with malignant tumors, phagocytic function decreased significantly. From November 1979 to June 1980, we detected the phagocytosis of macrophages in 34 patients with gynecological malignant tumors, and compared them to 39 cases of benign gynecologic tumors and 30 cases of non-tumor patients. In addition, some postoperative cases were tested, and preoperative