目的:探讨经皮冠状动脉介入治疗(percutaneous coronary intervention，PCI)术后微循环阻力指数(index of microcirculatory resistance, IMR)与左心室重构的相关性。方法:纳入2017年7月至2019年9月本院收治的204例行PCI的首次急性ST段抬高型心肌梗死(STEMI)患者，于术后第2天测其IMR值，以中位数为界值，将IMR<中位数设为A组，IMR≥中位数设为B组。随访6个月，比较两组患者主要心血管不良事件(major adverse cardiovascular cvent, MACE)发生情况和左心室重构指标情况。采用Spearman线性相关方程分析IMR与左心室重构指标的相关性，绘制Kaplan-Meier生存曲线，分析两组患者发生MACE的风险。结果:相比B组，A组有糖尿病史者占比、超敏C反应蛋白(hs-CRP)和尿素氮(BNP)水平均较低，侧支循环状况较好，差异均有统计学意义(均n P0.05)；两组患者术后LVEF、GWMI及RWM均较术前改善，且B组术后LVEDD及RWMI大于A组，LVEF小于A组，差异有统计学意义(均n P<0.05)。Spearman相关性分析显示，IMR与LVEDD(n ρ＝-0.756，n P<0.05)及LVEF(n ρ＝-0.648，n P<0.05)水平呈负相关。A组患者MACE总发生率明显低于B组，差异有统计学意义(n P<0.05)。Kaplan-Meier生存曲线分析显示，A组患者6个月MACE发生风险低于B组，差异有统计学意义(log-rankn χ2＝5.570, n P＝0.018)。n 结论:PCI术后IMR与患者左心室重构密切相关，IMR可较好地预测患者术后左心室功能和MACE发生情况。“,”Objective:To investigate the correlation between the index of microcirculatory resistance (IMR) and left ventricular remodeling after percutaneous coronary intervention (PCI).Methods:A total of 204 patients with first onset acute ST-segment elevation myocardial infarction (STEMI) undergoing PCI from July 2017 to September 2019 in our hospital were enrolled in this study, and the IMR was measured on the second day after the surgery. The patients were divided in to two groups according to the IMR(IMR