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目的总结颅内孤立性纤维瘤(intracranial solitaty fibrous tumor,ISFT)的MRI表现。方法回顾性分析2010年12月-2015年12月经病理证实的8例ISFT患者资料,并结合文献对其MRI表现进行研究分析。结果 8例患者肿瘤均为单发病灶,其中4例起自于小脑幕且位于幕下,2例位于桥小脑角区,1例位于颈静脉孔区,1例位于鞍区。8例患者肿瘤边界清楚,其中3例呈规则类圆形,2例形态欠规则,2例呈明显分叶状,1例呈哑铃型;肿瘤大小35~65 mm。5例患者肿瘤T1加权像(T1 weighted image,T1WI)呈等高混杂信号,T2加权像(T2 weighted image,T2WI)呈低信号;其余3例肿瘤实质部分T1WI呈等低信号,T2WI呈低信号,瘤内可见部分T1WI低信号,T2WI高信号且无增强效应的囊性区域。所有患者T2WI低信号区增强效应明显。6例可见血管流空效应,3例见瘤周水肿,8例患者均未见“脑膜尾”征。3例囊性变者经病理证实为恶性ISFT,其余5例为良性ISFT。结论 ISFT的MRI表现具有一定特征,瘤内囊性变和肿瘤恶性变之间可能存在关系,ISFT的诊断仍主要依赖于组织病理学检查。
Objective To summarize the MRI findings of intracranial solitaty fibrous tumor (ISFT). Methods The data of 8 patients with ISFT confirmed by pathology from December 2010 to December 2015 were analyzed retrospectively. The MRI findings were analyzed with the literature. Results The tumors of 8 patients were all single lesion, of which 4 cases originated from the tentorium of cerebellum and located under the screen, 2 cases were located in the cerebellopontine angle area, 1 case was located in the jugular foramen region and 1 was located in the saddle area. The tumor border was clear in 8 cases, of which 3 cases showed regular round shape, 2 cases had irregular shape, 2 cases showed obvious lobulation and 1 case showed dumbbell shape. The size of tumor ranged from 35 to 65 mm. The T1 weighted images of T1WI and T2WI T2WI showed low signal in 5 patients. The other T1WI showed low signal in T1WI and low signal in T2WI , The tumor can be seen in some T1WI low signal, T2WI high signal and no enhancement effect cystic region. All patients T2WI low signal area enhancement effect is obvious. 6 cases of visible vascular flow emptying effect, 3 cases of peritumoral edema, 8 patients were not seen “Meningeal ” sign. 3 cases of cystic degeneration confirmed by pathological malignant ISFT, the remaining 5 cases of benign ISFT. Conclusion The MRI findings of ISFT have certain characteristics. The relationship between cystic degeneration and malignant transformation of tumor may be related. The diagnosis of ISFT mainly relies on histopathological examination.