T及NK细胞淋巴瘤(T and natural killer cell lymphoma,T/NKCL)是一组生物学、组织学及临床特征异质性较大的恶性克隆增殖性疾病,占非霍奇金淋巴瘤的5%~20%,常与EB病毒(EBV)感染有关,在亚洲等地区相对高发,多数类型的临床表现呈侵袭性,治疗效果不佳~([1])。近年T/NKCL在分类、诊断和治疗方面有进展,本文简要综述如下。1分类的更新2016年WHO在原有2008版分类的基础上 T and natural killer cell lymphoma (T / NKCL) are a group of malignant clonal proliferative diseases with high heterogeneity in biology, histology and clinical features, accounting for 5% of non-Hodgkin’s lymphoma % ~ 20%, often associated with Epstein-Barr virus (EBV) infection, is relatively high in Asia and other regions, most types of clinical manifestations of invasive, poor treatment ~ ([1]). In recent years, T / NKCL in the classification, diagnosis and treatment progress, this article briefly summarized as follows. 1 classification update 2016 WHO in the original 2008 version of the classification based on