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目的:回顾1997/2007伊朗亚兹德地区的200例眼及附属器肿瘤的流行病学特征,确定肿瘤的人群分布及肿瘤位置。方法:回顾观察性病例报道。我们回顾1997/2007医院组织病理学确诊为眼眶肿瘤的病例,分析200例连续病例的年龄分布、病理学、肿瘤来源及肿瘤位置。结果:患者200例(男111例,女89例),其中110例(55.0%)为良性肿瘤,86例(43.0%)为恶性,4例(2.0%)为转移性肿瘤。119例(59.5%)为眼睑肿瘤,21例(10.5%)为眼眶,60例(30.0%)位于眼球。最常见的恶性肿瘤是基底细胞癌(BCC)(25.5%)、鳞状细胞癌(SCC)(6.0%)及黑素瘤(5.5%)。各种类型的痣(15.0%)、皮样囊肿(5.5%)、血管瘤(5.0%)是最常见的良性肿瘤。200例患者按年龄分为两组,18岁以上及18岁以下。18岁以下患者中,最常见的是良性肿瘤(90.1%),恶性肿瘤及转移性肿瘤分别占8.4%和1.5%。然而,18岁以上患者,常见的是恶性肿瘤(51.1%),良性肿瘤占47.1%,转移性肿瘤占1.8%。结论:眼眶肿瘤的病理学特征与患者的年龄及肿瘤在眼及附属器的位置有关。在进行活检及肿瘤切除术之前,患者的发病年龄和肿瘤位置可成为我们制定治疗方案的前提,也是预后评估的重要信息。
OBJECTIVE: To review the epidemiological characteristics of 200 cases of ocular and adnexal tumors in Yazd, Iran from 1997/2007 to determine the population distribution and tumor location of the tumors. Methods: Review observational case reports. We reviewed the 1997/2007 hospital histopathology diagnosed as orbital tumors, analysis of 200 consecutive cases of age distribution, pathology, tumor origin and location of the tumor. Results: There were 200 patients (111 males and 89 females), of which 110 (55.0%) were benign, 86 (43.0%) were malignant and 4 (2.0%) were metastatic tumors. 119 (59.5%) were eyelid tumors, 21 (10.5%) were eyes, and 60 (30.0%) were located in the eye. The most common malignancies were basal cell carcinoma (BCC) (25.5%), squamous cell carcinoma (SCC) (6.0%) and melanoma (5.5%). Various types of moles (15.0%), dermoid cysts (5.5%), hemangiomas (5.0%) are the most common benign tumors. 200 patients were divided into two groups according to their age, above 18 and under 18 years old. Of the patients under the age of 18, the most common were benign (90.1%), malignant and metastatic tumors accounted for 8.4% and 1.5%, respectively. However, malignant tumors (51.1%) were common in patients over 18 years of age, with benign tumors accounting for 47.1% and metastatic tumors accounting for 1.8%. CONCLUSIONS: The pathological features of orbital tumors are related to the age of the patient and the location of the tumor in the eye and appendage. Before the biopsy and tumor resection, the patient’s age at onset and location of the tumor can be a prerequisite for our treatment plan and an important prognostic assessment.