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目的探讨腹腔镜术后联合促性腺激素释放激素(GnRH)-a治疗子宫内膜异位症的临床疗效。方法选取珠海市妇幼保健院2011年1月至2013年1月间收治的子宫内膜异位症患者86例,经病理学诊断为子宫内膜异位症,随机分为观察组和对照组,观察组采用腹腔镜术后联合GnRH-a治疗,对照组单纯采用腹腔镜手术,观察两组术后2年内的疼痛缓解率、复发率、妊娠率。结果观察组42例患者中症状缓解率为85.71%(36/42),妊娠率为63.33%(19/30),高于对照组的63.64%(28/44)、43.75%(14/32),复发率为11.90%(5/42),低于对照组的29.55%(13/44)。结论腹腔镜手术联合GnRH-a治疗子宫内膜异位症疗效确切,可提高妊娠率,降低复发率,值得临床推广应用。
Objective To investigate the clinical efficacy of laparoscopic combined with gonadotropin-releasing hormone (GnRH) -a in the treatment of endometriosis. Methods 86 cases of endometriosis admitted to Zhuhai MCH from January 2011 to January 2013 were diagnosed as endometriosis by pathology and randomly divided into observation group and control group. The observation group was treated with laparoscopic combined with GnRH-a, while the control group with laparoscopic surgery alone. The pain relief rate, recurrence rate and pregnancy rate were observed within two years after operation. Results In 42 cases of observation group, the symptom relief rate was 85.71% (36/42) and pregnancy rate was 63.33% (19/30), which was higher than 63.64% (28/44) and 43.75% (14/32) in control group , The recurrence rate was 11.90% (5/42), which was lower than that of the control group (29.55%, 13/44). Conclusions Laparoscopic surgery combined with GnRH-a is effective in treating endometriosis, which can improve the pregnancy rate and reduce the recurrence rate, which is worthy of clinical application.