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在广西肝癌高发区壮族自然人群中采集血清标本１７７６人份，采用ＥＬＩＳＡ方法检测抗－ＨＣＶ、ＨＢｓＡｇ，ＰＣＲ技术检测ＨＣＶ－ＲＮＡ、ＨＢＶ－ＤＮＡ，并对ＨＣＶ－ＲＮＡ阳性的６９份标本采用型特异性引物进行基因分型。结果显示：（１）研究人群中ＨＣＶ－ＲＮＡ阳性率为３．８８％；（２）流行的ＨＣＶ基因以Ⅰ型或与其它型别的混合感染为主；（３）Ⅰ型感染者中ＡＬＴ的异常率高于其它型别的感染者；（４）当地ＨＣＶ伴随感染ＨＢＶ的现象比较常见。上述发现是否与当地肝癌高发有关，值得进一步研究
1776 serum samples were collected from natural populations of Zhuang population in high incidence areas of Guangxi liver cancer. Anti-HCV and HBsAg were detected by ELISA, HCV-RNA and HBV-DNA were detected by PCR, and 69 types of HCV-RNA positive samples were type specific. Sex primers are genotyped. The results showed that: (1) The positive rate of HCV-RNA in the study population was 3.88%; (2) The prevalent HCV genes were mainly type I or mixed infection with other types; (3) ALT in patients with type I infection The abnormal rate is higher than that of other types of infection; (4) The phenomenon of local HCV accompanied with HBV infection is more common. Whether the above findings are related to the high incidence of local liver cancer is worth further study