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目的:探讨黏液脓性宫颈炎(mucopurulent cervicitis,MPC)未愈患者行电凝治疗对术后出血及感染的影响。方法:回顾性分析因宫颈柱状上皮异位合并人乳头瘤病毒(HPV)感染自愿接受宫颈电凝治疗的384例患者的临床资料。其中,153例患者电凝治疗前无MPC(无MPC组),121例患者曾有MPC且电凝治疗前MPC已治愈(MPC治愈组),110例患者电凝治疗前MPC漏治(MPC漏治组)。比较3组进行宫颈电凝治疗的并发症。结果:1 MPC漏治组电凝治疗术中出血、术后出血、术后感染率分别为26.4%(29/110)、92.7%(102/110)、71.8%(79/110),较无MPC组的3.3%(5/153)、10.5%(16/153)、11.7%(18/153)及MPC治愈组的4.1%(5/121)、9.1%(11/121)、14.0%(17/121)均明显增加(P<0.05)。而无MPC组及MPC治愈组之间各指标的差异均无统计学意义(P>0.05)。2 MPC漏治组电凝治疗术后HPV转阴率、异位柱状上皮鳞化有效率分别为28.1%(31/110)、55.5%(61/110),较无MPC组的73.9%(113/153)、100.0%(153/153)及MPC治愈组的79.3%(96/121)、100.0%(121/121)均明显降低(P<0.05)。结论:MPC漏治容易造成电凝治疗后脱痂期出血及术后感染,降低HPV转阴率及柱状上皮异位痊愈率。
Objective: To investigate the effect of electrocoagulation therapy on postoperative bleeding and infection in patients with mucopurulent cervicitis (MPC). Methods: The clinical data of 384 patients who were voluntarily received cervical electrocoagulation for cervical heterotopic cervical HPV infection were retrospectively analyzed. Among them, 153 patients had no MPC (no MPC group) before electrocoagulation, 121 had MPC, and MPC had been cured before electrocoagulation (MPC-cured group), and 110 patients had missed MPC before electrocoagulation Governance group). The complications of cervical electrocoagulation were compared between the three groups. Results: 1 MPC leakage treatment group bleeding, postoperative bleeding, postoperative infection rates were 26.4% (29/110), 92.7% (102/110), 71.8% (79/110), respectively, compared with no 3.3% (5/153), 10.5% (16/153), 11.7% (18/153) in the MPC group and 4.1% (5/121), 9.1% (11/121), 14.0% 17/121) were significantly increased (P <0.05). There was no significant difference in the indexes between the MPC group and the MPC group (P> 0.05). The rate of HPV negative conversion and squamous ectopic columnar epithelium in the MPC group were 28.1% (31/110) and 55.5% (61/110), respectively, compared with 73.9% (113.9%) in the MPC group / 153), 100.0% (153/153) and MPC cured group (79.3%, 96/121) and 100.0% (121/121), respectively. CONCLUSION: Leakage of MPC easily leads to hemorrhage and postoperative infection after sclerosing, reducing the rate of HPV negative conversion and the recovery rate of columnar epithelium.