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[期刊论文] 作者:Ning Zhu,Jian Cui,Chunxia Qiao,Yan Li,Yuanfang Ma,Jiyan Zhang,Beifen Shen,
来源:中国免疫学杂志(英文版) 年份:2008
M-CSF is a key cytokine in macrophage development by inducing MAPKs activation, and cAMP can inhibit MAPKs activation induced by inflammatory stimuli. To explor...
In vitro molecular evolution of anti-Her2 antibody MILS using an computer-aided epitope-specific syn
[会议论文] 作者:Chunxia Qiao,Ming Lv,Zhou Lin,Longlong Luo,Jing Geng,Yan Li,Jiannan Feng,Beifen Shen,
来源:第六届全国生物治疗学术大会 年份:2012
Increased affinities mainly equals to improved biological efficacy in many cases.By now display methods including phage library are widely exploited to obtain higher affinity antibodies.Traditional li...
Affinity maturation of antiHER2 monoclonal antibody MIL5 using an epitope-specific synthetic phage l
[会议论文] 作者:Chunxia Qiao,Ming Lv,Xinying Li,Jing Geng,Yan Li,Jiyan Zhang,Zhou Lin,Jiannan Feng,Beifen Shen,
来源:第七届国际分子模拟与信息技术应用学术会议 年份:2014
Increased affinities mainly equal to improved biological efficacy in many cases.By now, display methods including phage library are widely exploited to obtain higher affinity antibodies.Traditional li...
[期刊论文] 作者:Hao Liu,Chunxia Qiao,Naijing Hu,Zhihong Wang,Jing Wang,Jiannan Feng,Beifen Shen,Yuanfang Ma,Longlong,
来源:工程(英文) 年份:2021
Immunotherapy with anti-programmed cell death protein-1(PD-1)/programmed cell death ligand-1(PD-L1)monoclonal antibodies has become routine in the treatment of many kinds of human cancers,such as lung cancer,intestinal cancer,and melanoma.T......
[会议论文] 作者:Jiyan Zhang,Beifen Shen,Ning Zhu,Qingyang Wang,Jing Wang,Yuanfang Ma,Chunxia Qiao,Yan Li,Xinying Li,Bing,
来源:2010中国青年遗传学家论坛 年份:2010
Elevated IL-12 production and higher rate of CD4+ T conventional (Tconv) cell proliferation in NOD mice have been implicated in the progression of type 1 di...
A Single Chain Antibody using LoxP511 as the Linker Enables Large-Content Phage Library Construction
[会议论文] 作者:Yan Zhang,Chunxia Qiao,Jiannan Feng,Wei Wang,Ming Lv,Zhou Lin,Jing Geng,Yali Li,Beifen Shen,Yuanfang,
来源:第七届国际分子模拟与信息技术应用学术会议 年份:2014
To obtain natural or "me-better" antibodies (e.g., affinity-maturated antibodies), phage display libraries are widely used.However, the likelihood of obtaining satisfactory antibodies depends on the l...
[会议论文] 作者:Jing Yang,Ming Lv,Jiannan Feng,Qun Wang,Chunxia Qiao,Zhou Lin,Xinying Li,Yifei Huang,Tingting Zhou,Yan,
来源:第七届国际分子模拟与信息技术应用学术会议 年份:2014
Angiogenesis is crucial for tumor development, growth and metastasis.Vascular endothelial growth factor (VEGF) has been implicated in promoting sol id tumor growth and metastasis via stimulating tumor...
[会议论文] 作者:Longlong Luo,Chunxia Qiao,Jiannan Feng,Qun Luo,Leiming Guo,Ming Lv,Zhou Lin,Jing Geng,Xinying Li,Yan,
来源:第七届国际分子模拟与信息技术应用学术会议 年份:2014
Ricin is a highly lethal toxin.Anti-ricin chineric monoclonal antibody (mAb) C4Cl3 was prepared in our lab;however, its binding affinity was moch weaker than that of the parent antibody 4C13.In this s...
[期刊论文] 作者:Chunxia Qiao,Ming Lv,Xinying Li,Xiaoling Lang,Shouqin Lv,Mian Long,Yan Li,Shusheng Geng,Zhou Lin,Beifen,
来源:工程(英文) 年份:2021
Fully human antibodies have minimal immunogenicity and safety profiles.At present,most potential antibody drugs in clinical trials are humanized or fully human.Human antibodies are mostly generated using the phage display method(in vitro)or......
Characterization of a Novel Anti-DR5 Monoclonal Antibody WD1 with the Potential to Induce Tumor Cell
[期刊论文] 作者:Jing Wang,Zhou Lin,Chunxia Qiao,Ming Lv,Ming Yu,He Xiao,Qingyang Wang,Liyan Wang,Jiannan Feng,Beifen,
来源:中国免疫学杂志(英文版) 年份:2008
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